Dear SPM Community,
I have an experiment where the same subjects came in for two scans
(abstinent and satiated conditions), and reported craving levels on
both days. I'd like to calculate the difference in craving (abstinent
- satiated) with the difference in brain activity from the two
separate scans, and would like to do this in two ways:
1) By using whole brain data in SPM. I used a paired t-test with
change in craving as covariate, and then created a contrast that
looked only at the covariate to look at the effect of change in
craving. Is this correct?
2) By extracting ROIs from each subject and correlating those ROIs
with change in craving using a statistical program. In order to do
this, I was thinking of creating individual T maps for each subject
(abstinent scan - satiated), but a second level analysis in SPM does
not really seem to let me do that. Any suggestions on how to this?
Any help would be greatly appreciated!
Thank you!
Deborah Tang, Doctoral Candidate
McGill University
Montreal Neurological Institute
3801 University St, Room WB 214D
Montreal, QC H3A 2B4
Canada
Phone: (514) 398-6644 Ext. 089469
Fax: (514) 398-8948
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