I can't see anything wrong with the design and you said it worked with
other designs. My suggestion would be to start with a simple design:
two groups, then four groups, then add the covariates. This way you
can see at what point the model breaks.
One other thought is to close out of MATLAB completely, then try it
again. Occasionally, there will be things that hang in MATLAB and
cause odd behavior.
Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Postdoctoral Research Fellow, GRECC, Bedford VA
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Office: (773) 406-2464
=====================
This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED
HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is
intended only for the use of the individual or entity named above. If the
reader of the e-mail is not the intended recipient or the employee or agent
responsible for delivering it to the intended recipient, you are hereby
notified that you are in possession of confidential and privileged
information. Any unauthorized use, disclosure, copying or the taking of any
action in reliance on the contents of this information is strictly
prohibited and may be unlawful. If you have received this e-mail
unintentionally, please immediately notify the sender via telephone at (773)
406-2464 or email.
On Thu, Jun 30, 2011 at 1:51 PM, Rick White <[log in to unmask]> wrote:
> The design matrix is attached. I have already ran a second-level factorial
> design that uses the exact same images and the model was estimated
> successfully. Should I expect that a 1 sample t-test would not necessarily
> estimate even though a factorial design did?
>
> On Thu, Jun 30, 2011 at 1:37 PM, MCLAREN, Donald <[log in to unmask]>
> wrote:
>>
>> Can you attach a jpg of your design?
>>
>> Also, if you run a 1 sample t-test using all of these images, does the
>> model run? This would help determine if the problem is with the data
>> or the files.
>>
>> Best Regards, Donald McLaren
>> =================
>> D.G. McLaren, Ph.D.
>> Postdoctoral Research Fellow, GRECC, Bedford VA
>> Research Fellow, Department of Neurology, Massachusetts General Hospital
>> and
>> Harvard Medical School
>> Office: (773) 406-2464
>> =====================
>> This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED
>> HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is
>> intended only for the use of the individual or entity named above. If the
>> reader of the e-mail is not the intended recipient or the employee or
>> agent
>> responsible for delivering it to the intended recipient, you are hereby
>> notified that you are in possession of confidential and privileged
>> information. Any unauthorized use, disclosure, copying or the taking of
>> any
>> action in reliance on the contents of this information is strictly
>> prohibited and may be unlawful. If you have received this e-mail
>> unintentionally, please immediately notify the sender via telephone at
>> (773)
>> 406-2464 or email.
>>
>>
>>
>>
>> On Thu, Jun 30, 2011 at 1:10 PM, Rick White <[log in to unmask]>
>> wrote:
>> > I am attempting to set up 3 second-level PPI analyses using Group and
>> > Age as
>> > factors. Upon running the model estimation I receive this error:
>> >
>> > Warning: Please check your data: There are no significant voxels.
>> >> In spm_spm at 812
>> > In spm_run_fmri_est at 53
>> > In matlabbatch/private/cfg_run_cm at 29
>> > In cfg_util>local_runcj at 1363
>> > In cfg_util at 699
>> > In cfg_ui>MenuFileRun_Callback at 1156
>> > In gui_mainfcn at 96
>> > In cfg_ui at 53
>> > Failed 'Model estimation'
>> > Reference to non-existent field 'xKXs'.
>> > In file "/usr/local/spm/spm8/config/spm_run_fmri_est.m" (v3327),
>> > function
>> > "spm_run_fmri_est" at line 68.
>> >
>> > The following modules did not run:
>> > Failed: Model estimation
>> >
>> >
>> > There is nothing wrong with the individual contrast images that are a
>> > part
>> > of the design as I have looked at each individually and they are the
>> > exact
>> > same images used in a separate design.
>> >
>> > As a little background, I have set up second-level PPIs using group and
>> > hemisphere as the factors having created PPI's from peaks in the left
>> > and
>> > right hemispheres of the seed region. In these designs, I have set up
>> > Age as
>> > a non-orthogonalized covariate of interest and received significant
>> > results.
>> > In order to further characterize this age interaction, I used a group x
>> > age
>> > 2nd level PPI analysis, but using the PPI contrast image from the
>> > overall
>> > peak and split the subjects by their median age (young and old). In all
>> > of
>> > the designs, upon model estimation I am receiving the same error.
>> >
>> > Any suggestions/comments?
>> >
>> > --
>> > Rick White
>> >
>> >
>
>
>
> --
> Rick White
>
>
|