On 30 Jun 2011, at 01:42, Michael Thompson wrote:
> the introduction of a disulfide can create artificial "crystal contacts," which also aid in crystallization
Another example of this is described here:
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction.
Meenan NA, Sharma A, Fleishman SJ, Macdonald CJ, Morel B, Boetzel R, Moore GR, Baker D, Kleanthous C.
Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10080-5.
Huw
--
Dr Huw Jenkins
Astbury Centre for Structural Molecular Biology
University of Leeds
|