Dear SPMers,
we used fMRI to compare differences between one brain-lesioned patient and a group of 12 healthy controls. Findings from a pooled 2-sample t-test revealed two regions of higher activity in the patients within the task related network. It would be an interesting question to investigate whether these two regions were most strongly connected within the controls. Would a connectivity analysis incorporating only 12 subjects make sense? Are there other methodological approaches to test our hypothesis?
Thanks in advance & best regards,
Ben
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