Dear All,
I am playing around with scripting conjunction analyses as I want to
write out files I can use further. In this context, I am, for
completeness sake, trying to implement the global null approach. In a
message some time ago (09/19/2004), Tom suggested that the threshold
that should then be applied to each image individually is the assumed
significance, corrected for the number of effects ("If a0 is your
desired false positive rate, use (a0)^(1/K) where K is the number of
effects conjoined. For 0.05 and 3 effects this is 0.3684"). However,
this was stated in the context of FDR-corrected thresholds, and I
wondered if this is also true for uncorrected thresholds. Can anyone
confirm that this approach is generalizable?
Thanks in advance,
Marko
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PD Dr. med. Marko Wilke
Facharzt für Kinder- und Jugendmedizin
Leiter, Experimentelle Pädiatrische Neurobildgebung
Universitäts-Kinderklinik
Abt. III (Neuropädiatrie)
Marko Wilke, MD, PhD
Pediatrician
Head, Experimental Pediatric Neuroimaging
University Children's Hospital
Dept. III (Pediatric Neurology)
Hoppe-Seyler-Str. 1
D - 72076 Tübingen, Germany
Tel. +49 7071 29-83416
Fax +49 7071 29-5473
[log in to unmask]
http://www.medizin.uni-tuebingen.de/kinder/epn
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