Dear SPMers,
I am planning to do a voxel based morphometric study on the MRI scan of headache patients. I need your suggestion regarding the use of template image. We have 30 MRI data of the migraine patients. All are reported as normal. I want to find out changes (increase or decrease thickness) in certain brain region, for eg. hypothalamus by VBM procedure. To say increase or decrease in the thickness i have to compare the images with normal anatomical image (template). right? But I don't have normal subjects data. In such case what procedure should I follow to find out the structural changes in the brain? This is my first MRI study. So need your help.
And I need tutorial for ROI. If any one have this tutorial or any web link please send it to me.
Waiting for your reply
With thanks
Ramesh
Manipal University
India.
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