Do you have a list of dark-matter-aware PDB refinement programs?
Adding dark matter and refining in TNT or Xplor gives me exactly
the same R as without. Furthermore the final refined files have
lost the dark matter as far as I can see. This leads me to believe
these programs are completely ignoring the dark matter.
Ed
Ethan Merritt wrote:
> Hi to all on ccp4bb:
>
> What better day to announce the availability of a breakthrough technique
> in macromolecular crystallography?
>
> Given recent discussion and in particular James Holton's suggestion that
> the problem of disordered sidechains is a problem akin to the difficulty
> of describing dark matter and dark energy...
>
> I am happy to announce a new crystallographic tool that can improve your
> model by accounting for an often-neglected physical property. A detailed
> explanation, references, and a preliminary implementation of the program
> can be downloaded from
>
> http://skuld.bmsc.washington.edu/DarkMatter
>
> --
> Ethan A Merritt
> Karmic Diffraction Project
> Fine crystallography since April 1, 2011
> "What goes around, comes around - usually as a symmetry equivalent"
>
|