You can combine them together using the ccp4i task "Find or Match Laue group" which runs Pointless. This will also try to choose the Laue group and possibly the space group. If the space group is P21 2 21 (not chosen by mosflm which can only choose the Laue group), you can choose in Pointless to reindex to the "reference" setting P21 21 2 if you want, although the "standard" setting will be P21 2 21 if this gives you a < b < c. As far as I know, nearly all programs can use this setting (and those that can't should be changed so that they can). See the documentation for Pointless (and this BB passim)
There does seem sometimes to be problems about merging strong and weak data sets (high & low resolution) which I don't understand, but it's probably OK
Phil
On 22 Feb 2011, at 21:53, Huiying Li wrote:
> I have collected two sets of data, high-res and low-res, with the same crystal and integrated them separately with imosflm. Now I want to merge and scale the two MTZ files with Scala in ccp4i GUI. But I do not know how to input 2 MTZ files through the Scala input GUI window (under Data Reduction module, Scaleand Merge Intensities).
>
> Another question on reindexing:
> The space group for this data set output by imosflm is P21221, which is non-standard. How can I reindex this to P21212, using Sftools or other routine?
>
> Thanks for help.
>
> Huiying ___
> Huiying Li, Ph. D
> Department of Molecular Biology and Biochemistry
> Natural Sciences I, Rm 2443
> University of California at Irvine
> Irvine, CA 92697, USA
> Tel: 949-824-4322(or -1953); Fax: 949-824-3280
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