This should be entirely possible. Providing the inter-subject
alignment is accurate, then a single ROI across all subjects should
represent the same brain region in all those subjects.
Best regards,
-John
On 6 December 2010 07:23, Ben Becker <[log in to unmask]> wrote:
> Dear SPMers
> I'm using DARTEL & VBM to compare grey matter integrity in two groups of patients. Usually I work with functional Data sets. Is it appropriate to perform Roi-analyses on the VBM Data? Based on previous findings we have specific hypotheses (e.g. Hippocampal abnormalities). Would it be valid to specify anatomical rois using the wfu pickatlas and restrict group comparisons to Hippocampal regions?
> Thanks in Advance & Kind regards
>
> Ben
>
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