Generally, without fat sat signal from the skull can be seen inside the
brain, giving a quite obvious artefact. I'm not sure what effect it
would have on the activation, since the same artefact should be present
in all slices (there is no reason why it should appear correlated with
the paradigm).
I think that to cover the whole brain maintaining the same TR it would
be better to increase the slice thickness rather than eliminating fat
sat.
Laura
On Wed, 2010-10-27 at 12:44 +0200, Andre Szameitat wrote:
> Dear SPMers,
> we are planning an fMRI study at a remote site and they have told us
> that with a TR of 2 sec we could scan either 23 slices with fat sat or
> 30 slices without fat sat (1.5T Siemens Sonata). The data without fat
> sat would be noisier, but otherwise fine (however, they didn't
> quantify how much noisier). 7 additional slices are appealing, because
> we can't easily increase the TR and need whole brain analysis.
>
> Does anybody have experience with this issue? Is fat saturation
> standard so that it should always be used?
>
> Many thanks in advance,
> Andre
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