On 25/08/10 23:24, Garib Murshudov wrote:
> However 1) coot uses 2mFo-DFc maps
Typically yes, but it uses whatever Refmac (or other programs) provide
(of course)
> 2) you should be able to feed any map you want to coot
Yes.
> so it is nice place for experimenting this kind
> of calculation
Hopefully.
> 3) You may try to relax gemetry
R/RC -> Refinement Weight.
(I often change it to 6 (from 60) if I need to tighten things up.)
> 4) Usually if the
> model does not fit into electron density and programs do not want to
> correct it then there may be some fundamental problem in this part of
> the model
Agreed!
On 25/08/10 23:13, Hailiang Zhang wrote:
> Actually I tried coot real space refine zone, but the model seems not
> sliding into the best density map
Can you expand on that?
On 25/08/10 23:33, Pavel Afonine wrote:
> Compare slides #4 and #5:
> http://cci.lbl.gov/~afonine/rsr.pdf
>
>
Yes, slide 5 is what Coot uses.
Paul.
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