.
MEDICAL: RESEARCH :
MEDICAL: CONDITIONS: OBESITY :
CHILDREN: GIRLS :
MEDICAL: DISEASES: DIABETES :
RISK:
NIH Study Finds that Overweight Girls Who Lose Weight
Reduce Adult Diabetes Risk
Date: Thu, 27 May 2010 09:11:55 -0400
From: "NIH OLIB (NIH/OD)" <[log in to unmask]>
To: [log in to unmask]
Subject: NIH Study Finds that Overweight Girls Who Lose Weight
Reduce Adult Diabetes Risk
U.S. Department of Health and Human Services
NATIONAL INSTITUTES OF HEALTH NIH News
Eunice Kennedy Shriver
National Institute of Child Health and Human Development
(NICHD)
<http://www.nichd.nih.gov/>
For Immediate Release: Thursday, May 27, 2010
CONTACT:
Robert Bock
or
Marianne Glass Miller,
301-496-5133
e-mail:
[log in to unmask]
NIH STUDY FINDS THAT OVERWEIGHT GIRLS
WHO LOSE WEIGHT REDUCE ADULT DIABETES RISK
Overweight girls who lose weight before they reach adulthood greatly
reduced their risk for developing type 2 diabetes, according to
researchers from the National Institutes of Health and Harvard University,
who analyzed 16 years of data on nearly 110,000 women.
Type 2 diabetes is the most common form of the disease. It is marked by
high blood sugar levels and difficulties in the body's production or use
of insulin. Being overweight, exercising infrequently and having a family
history of diabetes are known to contribute to the risk of developing the
disease.
The findings were published online in Diabetes Care and will appear in the
June issue.
The study was conducted by researchers at the Eunice Kennedy Shriver
National Institute of Child Health and Human Development (NICHD). Along
with the NICHD, two other NIH institutes, the National Cancer Institute
and the National Institute of Diabetes and Digestive and Kidney Diseases
provided funding for the analysis.
The study followed 109,172 female nurses from 1989 to 2005, noting how
many developed diabetes during that time. An initial survey collected
information about the women's health, history and lifestyle habits. One
question asked them to pick which of a series of diagrams best matched
their body shape at ages 5, 10 and 20. The series of nine line drawings
depicted female silhouettes of different sizes, ranging from gaunt (size
1) to obese (size 9). The nurses were also asked to provide their height
and current weight and to estimate their weight when they were 18. Every
two years after the initial survey, the women submitted follow-up
information including whether they developed diabetes.
The researchers recorded a total of 3,307 cases of type 2 diabetes over
the course of the study and found that the nurses who were overweight as
girls were more likely to become diabetic as adults. Women who indicated
that their size at age 5 matched or exceeded the size 6 figure were more
than twice as likely to develop diabetes as those who recalled matching
the size 2 figure. The women indicating the size 6 or above at age 10 were
2.57 times as likely to develop diabetes as adults. Those who reported a
body mass index of more than 30 (considered obese) at age 18 were almost
nine times more likely to develop diabetes than their normal-weight
counterparts (BMI of 18-19).
BMI, or body mass index, is a standard measure of a person's build based
on their height and weight. A BMI between 18 and 24 reflects a healthy
weight. BMI calculators and additional information about maintaining a
healthy weight are available at:
<http://www.nichd.nih.gov/health/topics/Obesity.cfm>
In the study, the researchers also examined the combined effect of extra
weight at various ages. Compared with women who were not overweight at key
ages in childhood, adolescence and adulthood, those who indicated they
were overweight at all three ages were 15 times more likely to develop
diabetes. Conversely, women who recalled being overweight at age 10 but
not overweight as adults were no more likely to become diabetic than their
peers who had been normal-weight children.
"These findings suggest that ensuring that overweight kids reverse their
weight gain is critical to limiting their future risk of diabetes as
adults," said study author Edwina Yeung, Ph.D., of the NICHD Division of
Epidemiology, Statistics and Prevention Research.
When the women entered the study, they averaged 34 years old. At that
time, they were asked to recall their weight at age 18. The researchers
found that women who gained weight after age 18 also increased their
diabetes risk. Those who gained more than 25 pounds increased their
diabetes risk more than 20 times. On the other hand, women who recalled
being overweight or obese at age 18 and subsequently lost 10 pounds or
more decreased their risk by more than half, compared with overweight or
obese women who maintained that weight as an adult.
Other authors of the paper were Cuilin Zhang and Germaine M. Buck Louis of
the NICHD and Walter C. Willett and Frank B. Hu of the Harvard School of
Public Health, Brigham and Women's Hospital and Harvard Medical School.
The NICHD sponsors research on development, before and after birth;
maternal, child, and family health; reproductive biology and population
issues; and medical rehabilitation. For more information, visit the
Institute's Web site at
<http://www.nichd.nih.gov/>
The National Institutes of Health (NIH) -- The Nation's Medical Research
Agency -- includes 27 Institutes and Centers and is a component of the
U.S. Department of Health and Human Services. It is the primary federal
agency for conducting and supporting basic, clinical and translational
medical research, and it investigates the causes, treatments, and cures
for both common and rare diseases. For more information about NIH and its
programs, visit
<http://www.nih.gov>
##
This NIH News Release is available online at:
<http://www.nih.gov/news/health/may2010/nichd-27.htm>
Sincerely,
David Dillard
Temple University
(215) 204 - 4584
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<http://daviddillard.businesscard2.com>
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