THE UNIVERSITY OF LIVERPOOL
CENTRE FOR MEDICAL STATISTICS AND HEALTH EVALUATION
MEDICAL RESEARCH COUNCIL NORTH WEST HUB FOR TRIALS METHODOLOGY RESEARCH
PROJECT CO-ORDINATOR
£25,751 - £35,646 pa
You will work on a development project relating to enhancing the design of medical research studies. The selection of appropriate outcomes is crucial to the design of randomised controlled trials. The COMET (Core Outcome Measures in Effectiveness Trials) initiative, funded by the Medical Research Council, is an international network bringing together individuals and organisations interested in the development, application and promotion of such core outcome sets. You should be educated to degree level (or equivalent), demonstrate excellent project management skills and have an understanding and interest in the clinical research environment. The post is available for 1 year initially.
Job Ref: A-572405
Closing Date: 30 June 2010
For full details, or to request an application pack, visit www.liv.ac.uk/working/job_vacancies/
or e-mail [log in to unmask] Tel 0151 794 2210 (24 hr answerphone), please quote Job Ref in all enquiries.
Core Outcome Measures in Effectiveness Trials (COMET)
Systematic reviews of randomised trials are hampered by inconsistency in the patient outcomes assessed across the different studies. Many meta-analyses have to leave out key studies because the relevant outcomes were not reported. Much could be gained if each medical condition had an agreed minimum set of core outcomes that were measured and reported in all clinical trials. Systematic reviews and cross-study comparisons would be easier, the design of new trials would be simplified, and there would be reduced risk of bias from selective reporting of outcomes. Efforts are underway to achieve this. In January this year, the COMET (Core Outcome Measures in Effectiveness Trials) initiative was launched at a meeting involving journal editors, regulators, consumers, policy makers, trial funders, trialists and systematic reviewers. COMET is overseen by a management group (Professor Paula Williamson, Professor Jane Blazeby, Professor Doug Altman and Professor Mike Clarke) and you can find out more about COMET at http://www.liv.ac.uk/nwhtmr/comet/comet.htm
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