Thanks to several people for helpful comments to my question on the Proportion of MR in the PDB.
I got two very detailed responses one from the OCA team at the Weizmann which went to the Bulletin Board
"This is what OCA has: From un total of 64,623 PDB structure files,
30,784 have 'MOLECULAR REPLACEMENT' as Method for Structure Determination.
However, you must remember that we have a large number of false negatives
Several reasons:
- Only 47,557 structure files from the total of 64,623 report which
method was used for structure determination. For example, 1CRY whose
title reports using the MR method does not include the info in the
proper REMARK.
- Users are allowed to write almost anything as the METHOD USED TO DETERMINE
THE STRUCTURE, making it difficult an accurate report. OCA found PDB italian
speaking structure files reporting 'MOLECULARE REPLACEMENT' ...
This and other problems are being reported to RCSB."
and one from U of Virginia
"Based on information from Remark200 lines, 31761 structures were solved
using MR, what comprise for 56.8% of all X-RAY structures (55843).
Considering structures which were determined using 'primitive MR' the
number grows to 34949 (62.6%). There are also some structures determined
using combination of MR with SAD, MAD, SIR and MIR. If we would add them,
the number will increase to 35258 (63.1%)."
Thanks again
Nick
--
Prof Nicholas H. Keep
Executive Dean of School of Science
Professor of Biomolecular Science
Crystallography, Institute for Structural and Molecular Biology,
Department of Biological Sciences
Birkbeck, University of London,
Malet Street,
Bloomsbury
LONDON
WC1E 7HX
email [log in to unmask]
Telephone 020-7631-6852 (Room G57 Office)
020-7631-6800 (Department Office)
Fax 020-7631-6803
If you want to access me in person you have to come to the crystallography entrance
and ring me or the department office from the internal phone by the door
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