*A post-doctoral position *is available immediately in the group of
Laurent Terradot at the Institut de Biologie et Chimie des Protéines
(IBCP), Lyon, (http://www.ibcp.fr). We are interested in the
structure/function of protein complexes involved in /Helicobacter pylori
/pathogenesis. This bacteria is a major pathogen that causes human
diseases such as ulcers and gastric cancers. Several projects are
available in our laboratory to study 1) virulence factors/receptor
interactions (see Tosi /et al/., Febs L, 2009; Angelini /et al/., Febs
Journal, 2009; Jimenez-Soto /et al/., PloS Pathogens, 2009) and 2) DNA
replication regulation (see Natrajan et al., Mol. Microbiology, 2007;
Natrajan et al., PNAS, 2009). Part of the work will be carried out with
National and International collaborations.
The IBCP is well equipped for Molecular Biology, Biochemistry,
Bioinformatics and Structural Biology and belongs to a larger campus
(Lyon Biopole; Center for Infectiology), giving access to
state-of-the-art core facilities. The group has regular access to
synchrotron beam time and is ideally located one hour from the European
Synchrotron ESRF. Lyon is a vibrant, historical French city and is a
world-excellence center in Infectiology.
We are looking for enthusiastic and self-motivated individuals with a
strong background in protein purification for structural studies.
Experience in protein-protein interactions (Biacore, ITC, etc...) and/or
study of large complexes would be a plus. Knowledge in Macromolecular
Crystallography would be considered an advantage but is not mandatory as
training can be provided. Working language of the laboratory is English.
Starting date: *As soon as possible*.
Salary is according to the CNRS french guidelines and will depend on
experience.
Please send a cover letter, your CV and one (or more) reference letter
as a single PDF file to: *[log in to unmask]
<mailto:[log in to unmask]>
*
Deadline: May the 1st, 2010.
**
* *
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Laurent Terradot
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Institut de Biologie et Chimie des proteines
ATIP-CNRS Group
Structural Biology of Bacterial Macromolecular Complexes
UMR 5086 CNRS Université de Lyon
7, passage du Vercors
69367 Lyon cedex 07 FRANCE
tel: +33 (0) 472 72 2652
Fax: +33 (0) 472 72 2604
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