Dear Elanor et al,
On Mon, Mar 22, 2010 at 09:30:31AM +0000, Eleanor Dodson wrote:
> A peak in a self rotation does NOT mean you have a dimer or a trimer
> - just that one molecule in the asu can be related to another by the
> given operator.
Exactly - and sometimes even the notion of 'molecule' breaks down: the
self-rotation function couldn't care less about what we call
'molecule'. You can get peaks in the self-rotation function even if
only single molecule is present:
* one helix matches any other helix pretty well
* you can place a rough 2-fold axis into a beta-sheet
* two domains with a similar fold, TIM barrels ... etc
I guess that's why choosing the radii can be quite important.
Cheers
Clemens
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