Hi Sarah,
> Please could someone clear up my confusion!!!!
Will try :)
> I understand that the segmentation procedure includes bias correction and non-linear
> registration but can not seem to ascertain if there is any normalisation of tissue priors or
> original images before the iterative algorithm kicks in.
There is. Christian has a nice graphic on the principle approach of
unified segmentation on his website
(http://dbm.neuro.uni-jena.de/vbm/vbm5-for-spm5/), and if you check the
paper on unified segmentation (NI 2005) then you will see that it
changed rather dramatically since the original implementation, so I
would not refer to John's seminal paper from 2000 too much anymore.
Hope this helps,
Marko
--
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Marko Wilke (Dr.med./M.D.)
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Universitäts-Kinderklinik University Children's Hospital
Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
Hoppe-Seyler-Str. 1, D - 72076 Tübingen
Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
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