Hi Nicolaus, hi Sophie
... just to add my 2 cents on this:
> Another very important preprocessing step, which improved
> the accuracy of normalization enormously in our study, is roughly
> aligning the anatomy manually with the template. this can be done with
> the check reg& display function in spm8. This can become quite a
> hassle for huge datasets but it helps.
I agree that it helps but I suggest to try coregistering the anatomical
to a T1 template. This will in most cases do a very good job of aligning
the anatomical, providing good starting estimates. Works for me (and I
bet it beats doing it manually on 100+ scans :)
BTW, I guess by "normalizing" the anatomical you really mean "segmenting
it" and using those parameters? Just to clarify that as SPM8 still has a
"normalize" button but the parameters obtained from that must be
expected to be much less precise than those obtained during unified
segmentation.
Best,
Marko
--
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Marko Wilke (Dr.med./M.D.)
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Universitäts-Kinderklinik University Children's Hospital
Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
Hoppe-Seyler-Str. 1, D - 72076 Tübingen
Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
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