Thanks a lot for your explanations Marko!
This is really helpful :)
I'll start rigth now installing TOM...
Best wishes,
Álvaro
On Thu, 26 Nov 2009 11:50:41 +0100, Marko Wilke
<[log in to unmask]> wrote:
>Hi Alvaro,
>
>> -I downloaded TOM from your site some days ago, but I didn't try it yet
>> because I wanted to use SPM8. Then is it possible to generate the priors
>> with TOM and SPM5 and then use them in SPM8 (replacing the apriori folder
>> files), or should I process all the analysis with SPM5?
>
>There is no need to do that, you can use the templates generated in spm5
>in spm8. We are working on a dedicated TOM for spm8 but are not quite
>there yet. You should not replace any files coming with spm; instead,
>the segmenttion routines allow you to specify your own tissue
>probability maps. This is where you should select the custom priors.
>
>> I have read that it's possible to generate your own template using your own
>> T1 images, I'll try to do that.
>
>... if you have a large-enough sample. To anticipate the next question,
>nobody knows what "large enough" is, but I would go for triple-digit
>numbers if at all possible.
>
>> -Can I ask a couple of basic questions more?
>> Do researchers use "uncorrected" option when showing activation maps, or is
>> it more trustworthy to use FWE or FDR?
>
>You do several thousands of comparisons, so correcting for those massive
>numbers is required, in one way or another (search the list for "small
>volume correction", FDR, cluster extent...). As I said, you need to be
>able to justify what you do.
>
>> The voxel extent threshold sets the minimum size of the clusters that will
>> be shown. Does it work only after the statistical map is calculated, merely
>> not showing the clusters smaller than the value?
>
>Basically, it suppresses small clusters, but there are also approaches
>that combine cluster extent and voxel values, so there is no easy answer.
>
>> Have a nice day :)
>
>You too (all of you :)
>Marko
>
>--
>=====================================================================
>Marko Wilke (Dr.med./M.D.)
> [log in to unmask]
>
>Universitäts-Kinderklinik University Children's Hospital
>Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
> Hoppe-Seyler-Str. 1, D - 72076 Tübingen
>Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
>=====================================================================
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