Hi Alvaro,
> However, I am not sure of how should I install these templates on the spm8
> folder, or if it does actually work for the SPM8 version.
You _could_ use the CCHMC priors for segmentation in spm5/8 but I would
advise against it. First, they are smoothed, and second, they are not
the first choice anymore. Instead...
> How could I use CCHMC(or another) template to process pediatric functional
> data in SPM8?
I would recommend you check out the TOM toolbox, as described in Wilke
et al, NeuroImage 2008, 41: 903-913. I think we also have a preprint on
the IRC website at https://irc.cchmc.org/software/tom.php but if you
cannot get to it, let me know. The templates generated by the toolbox
are, in my humble opinion, far superior to what we generated some years
ago based on the CCHMC dataset. We are working on a dedicated spm8
version but for starters, the current version can be installed in spm5
and the priors can be supplied to unified segmentation (check the
extended option where it specifies the tissue priors).
> -I have another beginner's question in reference to the FWE threshold:
> Is the 0.05 value the commonly used, or can I change its value to discover
> truly activated areas not shown with it, knowing that the possiblity of a
> false positive increases by doing so?
There is no law requiring p = .05; it is a customary setting that you
can deviate from, but you better have a good explanation. Alternatively,
I like to use FDR correction, which is also built-in in SPM8 but
somewhat hidden (see
https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind0907&L=SPM&P=R360). It
emphasizes sensitivity while FWE emphasizes specificity (in other words,
FWE is far stricter).
> Thank you very much for all your posts and help, it's really nice to learn
> reading the list:)
You're welcome :) And: I fully agree!
Marko
--
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Marko Wilke (Dr.med./M.D.)
[log in to unmask]
Universitäts-Kinderklinik University Children's Hospital
Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
Hoppe-Seyler-Str. 1, D - 72076 Tübingen
Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
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