Hi,
I appologize for the simple question, but statistics are not my strength. I
have run the TBSS analysis and I want to investigate potential correlations
between FA values within each voxel of the FA skeleton and a single
behavioural measure. I have 3 groups (2 diseases, 1 control) and want to
correlate values within each of the disease groups separately. I am not
interested in the correlations for the control group. I have set up the
following design.mat and design.con files (simplified to show only 2 subjects in
each group). Are they appropriate for what I am trying to do? Rows 3-4
represent the controls. The values in EV3 and EV4 were demeaned within the
specific diagnosis.
EV1(disease group 1) EV2(disease group 2) EV3(beh. meas. dg1) EV4(beh.
meas. dg2)
1 0 0.26 0
1 0 -3.4 0
0 0 0 0
0 0 0 0
0 1 0 -4.3
0 1 0 4.68
I have set up 4 contrasts to test both positive and negative correlations
within each disease group:
1 0 1 0
1 0 -1 0
0 1 0 1
0 1 0 -1
And will use the following randomise command:
randomise -i all_FA_skeletonised -o tbss -m mean_FA_skeleton_mask -d
design.mat -t design.con -n 5000 -c 3 -T2 -V -D
Does this seem appropriate? Thank you so much for your help!
Take care,
Laura
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