Hi Alvaro,
> -I downloaded TOM from your site some days ago, but I didn't try it yet
> because I wanted to use SPM8. Then is it possible to generate the priors
> with TOM and SPM5 and then use them in SPM8 (replacing the apriori folder
> files), or should I process all the analysis with SPM5?
There is no need to do that, you can use the templates generated in spm5
in spm8. We are working on a dedicated TOM for spm8 but are not quite
there yet. You should not replace any files coming with spm; instead,
the segmenttion routines allow you to specify your own tissue
probability maps. This is where you should select the custom priors.
> I have read that it's possible to generate your own template using your own
> T1 images, I'll try to do that.
... if you have a large-enough sample. To anticipate the next question,
nobody knows what "large enough" is, but I would go for triple-digit
numbers if at all possible.
> -Can I ask a couple of basic questions more?
> Do researchers use "uncorrected" option when showing activation maps, or is
> it more trustworthy to use FWE or FDR?
You do several thousands of comparisons, so correcting for those massive
numbers is required, in one way or another (search the list for "small
volume correction", FDR, cluster extent...). As I said, you need to be
able to justify what you do.
> The voxel extent threshold sets the minimum size of the clusters that will
> be shown. Does it work only after the statistical map is calculated, merely
> not showing the clusters smaller than the value?
Basically, it suppresses small clusters, but there are also approaches
that combine cluster extent and voxel values, so there is no easy answer.
> Have a nice day :)
You too (all of you :)
Marko
--
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Marko Wilke (Dr.med./M.D.)
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Universitäts-Kinderklinik University Children's Hospital
Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
Hoppe-Seyler-Str. 1, D - 72076 Tübingen
Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
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