Applicants are invited for a post doctoral position at the Carlsberg 
Laboratory to study structure and activity of starch branching and 
debranching enzymes during barley grain filling and germination.

The amount and quality of starch in barley are controlled by the enzymes 
involved in its biosynthesis; among them the branching (BE) and 
debranching enzymes (DBE). DBEs play an additional role during 
mashing/malting, since the fermentability of starch relies on this 
activity to degrade the α-1,6 branches of amylopectin. The aim of the 
present project is to characterize differences in BE and DBE activities 
in barley landraces during grain filling and germination and to seek to 
correlate these differences with exogenous proteins and with 
structural-functional properties of specific BE and DBE. Methods 
employed will include protein-protein interaction proteomics, 
enzymology, X-ray diffraction analysis of starch and protein. Our 
laboratory is fully equipped for all aspects of molecular biology, 
protein chemistry, protein crystallography and biophysical 
characterization of proteins.
Applicants must have experience with proteomics, enzymology and/or 
biophysical characterization of proteins. Experience with production and 
purification of recombinant proteins will be considered an advantage. 
The position is a three-year position with one-year contract 
re-negotiation. Inquiries should be directed to: Anette Henriksen, 
E-mail: [log in to unmask] To apply, please send a CV including a brief 
description of research interests and accomplishments, and the names and 
addresses of two referees to: Anette Henriksen, Protein Chemistry Group, 
Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Copenhagen, 
Denmark E-mail: [log in to unmask]

The Protein Chemistry Group at Carlsberg Laboratory studies starch 
metabolism from a structural-biochemical perspective. The Laboratory was 
set up in Copenhagen 1875 by the founder of Carlsberg to develop a 
scientific basis for malting, brewing, and fer­men­ting operations, and 
it has a long record in protein chemistry, yeast biology and plant 
physiology.

-- 
Anette Henriksen, Prof., Ph.D.
Carlsberg Laboratory, Biostructure Group,
Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.
Phone: +45 33275222. Fax: +45 33274765



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