> If you have non-crystallographic symmetry the effects are uncertain,
but
> in many cases this too gives you a lower than expected FreeR value,
and
> again, that doesnt mean you have a better structure..
>
> In general the difference in R and Rfree should be correlated with the
> resolution, but there doesnt seem to be any absolute level of
> expectation; thee are toomany other variables to consider..
> Eleanor
I agree: in simple cases with good medium-high res data, given Rwork you
can predict Rfree within the expected error in Rfree (based only on the
size of the test set). The problem is that real life is never simple! -
and NCS really messes things up!
Cheers
-- Ian
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