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ALLSTAT  September 2009

ALLSTAT September 2009

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Subject:

JOB: PhD Studentship in the Netherlands

From:

Renee Menezes <[log in to unmask]>

Reply-To:

Renee Menezes <[log in to unmask]>

Date:

Mon, 28 Sep 2009 10:19:14 +0100

Content-Type:

text/plain

Parts/Attachments:

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text/plain (74 lines)

PhD position in high-dimensional data analysis, The Netherlands

Institution: VU University Medical Center, Amsterdam
Department/section: Epidemiology and Biostatistics, Division VI
Working hours: 36 hours per week

General
The Biostatistics group (see http://www.vumc.nl/afdelingen/EB/ - in Dutch)
at the VU University Medical Center (VUmc, Amsterdam) has a small and very
active group of statisticians working on high-dimensional data analysis,
where Renée Menezes (the project leader) is based. The group within the
Department of Epidemiology & Biostatistics has close links to the
Mathematics and Statistics Department of the Vrije Universiteit, as well as
to both the Department of Pathology and the Microarray Facility of the VUmc. 

Project
High-dimensional data analysis, involving data with few samples (n) and many
more parameters (p>>n), is a fast-moving and competitive area of research.
This project aims at tackling the important problem of joint analysis of
such datasets, extending the work of Menezes et al (2009, BMC
Bioinformatics) to, amongst other things, find associations between multiple
high-dimensional genetic datasets (say, methylation, copy number and
expression array data), use gene sets in both dependent and independent
parts of the model to gain power in a similar way as done by Goeman et al
(2004, Bioinformatics), and to draw on these tools for better classification
of samples.

This project involves a collaboration with Jelle Goeman, of the Department
of Biostatistics of the Leiden University Medical Center (LUMC) and with the
internationally known Pediatric Oncology group of the Sophia Children’s
Hospital, Rotterdam, from which data will be analysed. So it will include
the student in an important network of scientists. 

Requirements
We are looking for a PhD student with an MSc in either Statistics,
Bioinformatics or a closely related discipline. Essentials are: good
statistical knowledge enabling the development of new models and analysis
tools, programming skills, the ability to explain complex ideas to
biologists/non-specialists and an affinity with genetics and biology.
Previous knowledge of any of the areas involved in the project (such as
mixed-effects models, high-dimensional data analysis) and of R programming
are an advantage. The PhD student we are looking for has good communication
skills and is flexible to work both at the VUmc and at the LUMC.

Work conditions 
This PhD position is open at the department of Epidemiology & Biostatistics.
The temporary employment will be for a period of 4 years. The gross salary
per month will be according to the AIO scales, depending on previous
experience. The terms of employment will be in accordance with the CAO
Universtair medische centra of the Netherlands.

Contact For details about the project contents please contact
Renee Menezes		Jelle Goeman
[log in to unmask]		[log in to unmask]
+31 20 444 4933		+31 71 526 9708

Applications
You may apply via our website or per conventional post. Via our website, go to
http://www.vumc.nl/afdelingen/werk/vacatures/overzicht/

and look for this job opening (“Vacatures”) under the “Beroepsgroep”
“Wetenschappelijk onderzoeker”. At the bottom of the screen, go to
“Soliciteren” and fill in the online form. As this is all in Dutch,
foreigners may prefer to apply via conventional post. For this, please send
your CV and motivation letter indicating the job opening number D6.2009.00085
 to

Divisiebureau divisie 6
mw. C. Egberts
Bs 7, C 369
[log in to unmask]

Closing date for applications : 19th October 2009

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