And I apologize for being crabby about it. I realize its hard
for people from different traditions and different native
tongues to figure out the best way to start an English letter
to people you've never met.
---- Original message ----
>Date: Fri, 21 Aug 2009 16:50:28 -0000
>From: Debajyoti Dutta <[log in to unmask]>
>Subject: [ccp4bb] I apologize
>To: [log in to unmask]
>
> Hi everybody,
>
> I really apologize to every members of CCP4BB for
> not to give attention to my addressing phrase. It is
> truly misleading. I swear not to make such bad
> mistake in future. I am really ashamed for such a
> deed.
>
> Sincerely
> Debajyoti Dutta
>
> On Fri, 21 Aug 2009 21:29:23 +0530 wrote
> >Dear Sir,
> Please don't assume that all crystallographers are
> male.
>
> ---- Original message ----
> >Date: Thu, 20 Aug 2009 16:45:55 -0000
> >From: Debajyoti Dutta
> <[log in to unmask]>
> >Subject: Re: [ccp4bb] cyseteine modification
> >To: [log in to unmask]
> >
> > Dear Sir,
> >
> > Thank you all who have replied. I jast want to
> > enquire that if there is any option in coot to
> > introduce the OH bond with Cys residue as well as
> to
> > introduce the secondary peptide like bond between
> > carboxylic carbon with amino group of lys.
> >
> > Sincerely
> > Debajyoti Dutta
> >
> > On Wed, 19 Aug 2009 20:58:44 +0530 wrote
> > >
> >
> > Dear Debajyoti
> >
> > There is also the sulfenic acid species (-S-OH)
> > which is actually
> > the first oxidized form of sulfhydryls on the way
> to
> > sulfonic acid. However
> > sulfenic acids are very susceptible to further
> > oxidation to sulfinic and sulphonic
> > acids, and therefore need a protective chemical
> > environment to remain stable.
> >
> > See for example some previous work of ours on
> > sulfenic and
> > sulfinic forms of active-site cysteines in
> > glutathione reductase (Nature
> > Structure Biology vol 5, 267-271, 1998) and the
> > corrresponding pdb entries 1dnc
> > and 1gsn.
> >
> > Best regards
> >
> > Savvas
> >
> > ----
> > Savvas Savvides
> > L-ProBE, Unit for Structural Biology
> > Ghent University
> > K.L. Ledeganckstraat 35
> > 9000 Ghent, BELGIUM
> > office: +32-(0)9-264.51.24 ;mobile:
> > +32-(0)472-92.85.19
> > Email: [log in to unmask]
> > http://www.lprobe.ugent.be/xray.html
> >
> > From: CCP4 bulletin board
> > [mailto:[log in to unmask]] On Behalf Of
> > Debajyoti Dutta
> > Sent: Wednesday, August 19, 2009 4:42 PM
> > To: [log in to unmask]
> > Subject: [ccp4bb] cyseteine modification
> >
> > Dear Sir,
> >
> > Is there any other oxidation states of cysteine
> > other than cysteine sulphinic
> > acid and cysteine sulphonic acid. In my protein,
> the
> > cysteine molecule is
> > definitely overoxidized but the electron density
> is
> > not corresponding to the
> > sulphinic or the sulphonic acid. The positive
> > density looks as if it can
> > accomodate only one oxygen atom and not more.
> >
> > Thank you for reply in advance.
> >
> > Sincerely
> > Debajyoti Dutta
> >
> > >
> > >E-mail message checked by Spyware Doctor
> > (6.1.0.447)Database version:
> >
> 6.13080http://www.pctools.com/spyware-doctor-antivirus/
> >
> > [IMG]
> Phoebe A. Rice
> Assoc. Prof., Dept. of Biochemistry & Molecular
> Biology
> The University of Chicago
> phone 773 834 1723
>
http://bmb.bsd.uchicago.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=123
>
> RNA is really nifty
> DNA is over fifty
> We have put them
> both in one book
> Please do take a
> really good look
> http://www.rsc.org/shop/books/2008/9780854042722.asp
>
> [IMG]
Phoebe A. Rice
Assoc. Prof., Dept. of Biochemistry & Molecular Biology
The University of Chicago
phone 773 834 1723
http://bmb.bsd.uchicago.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=123
RNA is really nifty
DNA is over fifty
We have put them
both in one book
Please do take a
really good look
http://www.rsc.org/shop/books/2008/9780854042722.asp
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