>Hi,
Sorry to bug you again. I am doing research on children and want to know
longitudinal changes in brain volume. The problem, that the patients are
very young (mostly under 5) and we do not have completely age matched
controls to create a template. Is it a possible sollution to create a
study-specific template (averaging the involved patients) brain and edges
file from them and use it for the "siena_flow2std A B" step and also in
'randomise' later. How can I make the program use another standard brain
instead of the MNI? The other question: Can I compare single time-point
brain volumes to an age matched control-group (standard brain, created
from them) (so not 2 time point comparison)?
Regards,
Balint Alkonyi
Detroit, US
Hi,
>
> yes - you can!;) However, you will need to create a edge mask in standard
> space of your kids template. I think there is a make_edges (or something
> like that) script somewhere in the distribution that tells you how to do
> it. You may also look at our 2007 Brain paper because it was quite
> explicit on that. Then have a look at the siena_flow2std script and edit
> the relevant calls.
> Hope that makes sense.
> Cheers-
> Andreas
>
> ________________________________________
> Von: FSL - FMRIB's Software Library [[log in to unmask]] im Auftrag von
> Balint Alkonyi [[log in to unmask]]
> Gesendet: Montag, 29. Juni 2009 22:47
> An: [log in to unmask]
> Betreff: [FSL] SIENA
>
> Is it possible to run SIENA on children using a template other than
> MNI152. If I
> am right in the voxelvise SIENA statistic part ("siena_flow2std a B"
> command)
> it uses the MNI 152 standard brain automatically. If I had a child
> template,
> could I run the procedure? Could someone help me?
>
> Many thanks in advance,
>
> Balint Alkonyi
>
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