Dear SPMers
I am preparing a data processing pipeline for VBM analysis of paediatric
data (7-12 year old boys). I created a custom templates (tissue probability
maps / priors) and understand that these must be set in the "Tissue
probability maps" option in either VBM5.1 toolbox or in the Segment routine.
However, I don't quite understand the impact of affine regularisation. It
seems the only choices for this option are "ICBM European brains," "Asian
brains", "average" or none. I have a small group of participants (10
patients, 10 controls). Affine regularistation to the "average" seems wrong
given that I've taken the careful step of creating age appropriate tempaltes
with TOM.
Two questions:
1. What is the best option for me?
2. Does it even matter if I ultimately end up using the "modulated
normalised non-linear only" images for my statistical analysis?
Cheers and thanks in advance,
Deryk
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