Hi,
I'm doing my first analysis using using probtrackx. I was hoping to compare the ROIs generated from tracking in a common space. I've thresholded them in a way that accounts for variation in "trackability." I'm trying to determine the appropriate DOF for my registration to compare overlap.
I'm wondering why the standard DOF for registration is 12. Doesn't that drastically change the size and shape of your ROIs, effectively diminishing individual variation?
To compare the size/overlap of tracts I think that I would do a 7 or 9 DOF to control for total brain size, but not distort the tract ROI too much. Is my logic right or are there good reasons to do a 12 DOF registration?
Thanks for the help!
Dylan
Dylan Alegria
CIBSR Imaging RA
Stanford University
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