Hi Haakon,
I did fMRI analysis on primary auditory cortex using SPM2's
normalization, unified segmentation (SPM5) and DARTEL. Comparing the
results, DARTEL performed better than SPM2, but not significantly
different than unified segmentation in terms of t-stats and functional
activation localization. I would say it is worth a try.
Good luck,
Amir
Marko Wilke wrote:
> Hi Haakon,
>
> just a short hint that regarding your first question, there was a
> paper in the last (I think) NeuroImage that dealt with the accuracy of
> spatial normalization, and DARTEL performed pretty well when compared
> with about 10 other algorithms, including spm2, spm5, and unified
> segmentation in spm5.
>
> Best,
> Marko
>
> Haakon Engen schrieb:
>> Dear fellow SPM'ers,
>>
>> I am currently setting up a preprocessing pipeline for a group of 40
>> subjects.Normalization is rather important for this project, seeing as
>> how I am planning to do DCM modeling on rather small subcortical ROI's.
>> I am therefore considering using DARTEL to spatially normalize my fMRI
>> volumes. My initial test runs have been successful, but it has dawned on
>> me that DARTEL normalization takes quite a bit longer than standard
>> normalization.
>>
>> I was therefore wondering if any of you have experience with DARTEL
>> normalization and could inform whether or not it is worth the extra
>> processing time, with regards to accuracy
>>
>> Second I have some questions regarding the precise procedure of doing
>> DARTEL with regard to fMRI normalization. Is it necessary to calculate
>> the Templates and flow fields for each subject, or should I include all
>> the GM and WM segmented images for all subjects in one calculation?
>>
>> Thanks in advance,
>> Haakon Engen
>> Graduate student/Research Assistant
>> University of Oslo, Norway
>>
>
--
________________________________
Amir M. Tahmasebi
Ph.D. Candidate,
Medical Image Analysis Lab.
School of Computing,
Queen's University,
Kingston, Ontario
CANADA
K7L 3N6
________________________________
Tel: (613) 533-2797
Web: www.cs.queensu.ca/~tahmaseb
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