For the first part of your question, I usually use sftools from the command 
line to combine things from different MTZ files, so you could give that a 
try if cad is giving you trouble.

For the second part of the question, if you're staying within CCP4, then 
cphasematch is probably the program you want, as it checks for origin 
shifts for you. Similar things can be done in Resolve or in the phenix tool 
get_cc_mtz_mtz (which uses Resolve).

Regards,

Randy Read

On Apr 11 2009, hari jayaram wrote:

>Hi
>I have multiple phase sets from separate sharp ( experimental phasing) and
>phaser molecular replacement runs. I have the values as hendrickson latman
>coeffs as output by phaser and sharp.
>I am imagining i can use phistats to compare these phase sets which are
>probably on different origins .
>
>The first problem I have is that i need to combine the multiple HLA files
>from a couple of mtz files into one mtz file for input to phistats .
>I am trying this with cad and I get the error in ccp4-6.0.99e "At line 869
>of file /home/hari/ccp4-6.0.99e/src/cad.f
>Fortran runtime error: End of record "
>
>I am hoping that cad can blindly take mtz columns from these files and put
>them into the same file .
>My questions are :
>How can I put these multiple sources of phases into one file . My second
>question is what is a good way to compare these phase sets .
>
>The detailed error from cad is reproduced below
>
>Thanks for your help
>hari
>
>
>***************************************************************************
>* Information from CCP4Interface script
>***************************************************************************
>The program run with command: /home/hari/ccp4-6.0.99e/bin/cad HKLIN1
>"/home/hari/newtry/gio_12.1.mtz" HKLIN2
>"/home/hari/AdiC/eden_flat_75.0pc.mtz" HKLOUT
>"/home/hari/newtry/phasereden.mtz"
>has failed with error message
>At line 869 of file /home/hari/ccp4-6.0.99e/src/cad.f
>Fortran runtime error: End of record
>***************************************************************************
>