Hi - please see Tom Nichols' recent posting on this on the FSL list.
Cheers.
On 16 Mar 2009, at 11:42, Silviu Podariu wrote:
> Hello,
>
> Suppose a smaller pool of subjects is available for a VBM/VBD study
> than one
> would normally need for a two-groups t-contrast to be significant.
> Is it
> possible to run a different sort of analysis in which one compares one
> single subject against the rest of the group?
>
> If 'yes', how would the statistical analysis be done in such a case?
> Our
> common sense feeling is that one should not attempt the same two-group
> procedure (with a design matrix having n_1 = 1 and n_2 = n-1, n
> being the
> total group size).
>
> Thank you,
> Silviu Podariu
> UNMC
> Omaha, NE
>
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