Dear All,
Just to clarify that I completely agree with the interest and
relevance of the two papers discussed in the News & Views and with 99%
of the News & Views article itself - it is just that readers from non-
structural biology fields may get the wrong impression from the 2
"was" words in the introductory paragraph...
And these wrong impressions are all too common, at least around here.
As another example, more than once I have been asked by someone if
they give me the sequence or name of a protein (even membrane
proteins), how many days would it take us to provide them the crystal
structure.
Mark
Mark J. van Raaij
Dpto de Bioquímica, Facultad de Farmacia
Universidad de Santiago
15782 Santiago de Compostela
Spain
http://web.usc.es/~vanraaij/
On 12 Mar 2009, at 21:57, Felix Frolow wrote:
> Dear Mark
> Stay calm
> Buzz-words come and very frequently do not stay, they go away with
> the artifacts they advocate...
>
> Dr Felix Frolow
> Professor of Structural Biology and Biotechnology
> Department of Molecular Microbiology
> and Biotechnology
> Tel Aviv University 69978, Israel
>
> Acta Crystallographica D, co-editor
>
> e-mail: [log in to unmask]
> Tel: ++972 3640 8723
> Fax: ++972 3640 9407
> Cellular: ++972 547 459 608
>
> On Mar 12, 2009, at 6:14 PM, Mark J. van Raaij wrote:
>
>> Dear All,
>>
>> a News & Views article in Nature 458, pages 37-38 of 5 March 2009
>> (link below) states:
>> "The development of structural biology WAS historically based on
>> the principle of divide and conquer — individual proteins were
>> purified to homogeneity and their atomic structures were solved in
>> vitro by using either X-ray crystallography or nuclear magnetic
>> resonance (NMR) spectroscopy. This approach WAS tremendously
>> successful, and led to the creation of a protein-structure databank
>> that currently contains more than 50,000 structures."
>>
>> I find the past tense here too much...
>>
>> Greetings,
>>
>> Mark
>>
>> Mark J. van Raaij
>> Dpto de Bioquímica, Facultad de Farmacia
>> Universidad de Santiago
>> 15782 Santiago de Compostela
>> Spain
>> http://web.usc.es/~vanraaij/
>>
>> http://www.nature.com/nature/journal/v458/n7234/full/458037a.html
>> Structural biology: Inside the living cell
>
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