Dear colleagues,
last year, we proudly announced
LI-Tool
an spm-compatible toolbox to assess lateralization in imaging data.
Since then, more than 150 scientists from all over the world have
requested the toolbox (and most seem to have found it useful :) As a
reminder, here's an abbreviated list of features:
- it allows to assess laterality based on standard anatomical delineations;
- it allows to exclude regions from processing;
- it offers several ways to threshold the input images (fixed, adaptive,
ranking, no threshold);
- it allows to create laterality curves (LI versus threshold),
optionally using a bootstrapping approach;
- it will take into account the number of voxels the result is based on,
and will abort when a critical number of voxels is not found;
- it works on normalized and (most) native-space images;
- unattended processing of an unlimited number of contrast images is
possible;
- it comes as a toolbox and thus runs within the familiar SPM GUI;
- it is still free :)
We are now advancing to version 1.1, and we believe that the following
features, several of which are based on user feedback (thank you
again!), warrant an official recommendation to update:
- the toolbox can now be scripted so you can run a complete analysis
from the command line without the need for user input, for example as
part of your routine analysis batch script;
- improvements have been made to the "silent mode", i.e., no more
windows popping up when analyzing 1000+ images;
- the output file has been updated, and the name of the output file can
now be customized, for example to include the current date or the
project name;
- compatibility has been extended to include spm8b, including a more
graceful handling of *.nii-files;
- a couple of minor nuisances were fixed (none of them critical, see the
accompanying history.txt for more details);
Updates were already sent to all registered users whose e-mail still
worked. All others, and everybody else who is interested in trying it
out, is encouraged to contact us at
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and I will gladly send you the link to the download location (please
include your professional affiliation information as we would like to
keep track of who is using it where. ). While we believe that the
toolbox is generally useful, we still take absolutely no responsibility
for its actions (there is of course an official disclaimer in the
documentation but I will not bore you by pasting it here :). We do not
have many ressources to officially support this project, but we will try
to be helpful.
Best wishes from Tuebingen,
Marko Wilke
PS: I realize this is shameless self-advertizing, sorry about that :)
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Marko Wilke (Dr.med./M.D.)
[log in to unmask]
Universitäts-Kinderklinik University Children's Hospital
Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
Hoppe-Seyler-Str. 1, D - 72076 Tübingen
Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
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