Dear Stasticians,
I have the following questions:
1-what are the issues that might rise when overpower our primary endpoint in CT.
2- could we perform an interim analysis to increase our sample size in CT.
3- I want to perform a cross over trial. how can calculate the sampel size?
4- why we attend to perform non-inferiority trial rather than equivalence.
Many thanks in advance for your reponse.
Abdallah
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