Thanks Peter!
Alwasy very gratefull!
Markus
Quoting Peter Kochunov <[log in to unmask]>:
> Gd shortens T2* fairly dramatically. So any sequence that is sensitive
> to the T2* will show the presents of Gd and will be susceptible to
> changes in its concentration.
> These effects will generally be contained to the compartment to where
> Gd is present e.g. vasculature. In fMRI experiment, Gd-contrast will
> increase the "BOLD" contrast, however, since most of the Gd contrasts
> have short elimination times and steep curve it is very hard to use,
> constructively. So my advice would be to do fMRI before contrast
> injection.
> pk
>
> ----- Original Message ----- From: "Markus Gschwind"
> <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Wednesday, April 23, 2008 9:24 AM
> Subject: [FSL] EPI is it sensible to gadolinium?
>
>
>> Hi!
>>
>> This is a question for the radiologist under the FSL people, sorry!
>>
>> Does anybody know if the contrast agent Gadolinium influences the
>> images of a subsequent fMRI acquistion?
>>
>> Appearently there is no influence in DWI (Stroke.
>> 2002;33:1799-1802), but on the other side there is Gado enhanced
>> EPI imaging for all sort of tumors etc.
>>
>> We will scan patients with both structural (with contrast) and
>> functional images and the best would be if we could do the
>> functional part while waiting the 15 minutes for the post contrast
>> T1 in order to safe time.
>>
>> Does anybody know?
>>
>> Very grateful!
>> Markus
>>
>> --
>>
>> Dr. med. Markus Gschwind, M.D.
>> Laboratory for Neurology and Imaging of Cognition
>> Dept of Neurosciences
>> University Medical Center (CMU)
>> 1 Michel-Servet - 1211 GENEVA - CH
>>
>> Tel 0041 (0) 22 379 5324
>> Fax 0041 (0) 22 379 5402
>> email: [log in to unmask]
>> http://labnic.unige.ch
>>
--
Dr. med. Markus Gschwind, M.D.
Laboratory for Neurology and Imaging of Cognition
Dept of Neurosciences
University Medical Center (CMU)
1 Michel-Servet - 1211 GENEVA - CH
Tel 0041 (0) 22 379 5324
Fax 0041 (0) 22 379 5402
email: [log in to unmask]
http://labnic.unige.ch
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