Hi,
Thanks for your reply. I looked at some of your past threads and created
the design matrix and contrast files. We are comparing two groups with age
as a covariate. The covariate values in the EV3 (third column) are demeaned.
Kindly check whether my design files are correct. Thanks.
Contrast file:
/ContrastName1 group mean
/ContrastName2
/NumWaves 3
/NumContrasts 2
/PPheights 1.569813e+00 1.569813e+00
/RequiredEffect 4.620 4.620
/Matrix
1.000000e+00 -1.000000e+00 0.000000e+00
-1.000000e+00 1.000000e+00 0.000000e+00
Matrix file:
/NumWaves 3
/NumPoints 23
/PPheights 1.000000e+00 1.000000e+00 1.000000e+01
/Matrix
1.000000e+00 0.000000e+00 3.000000e-01
1.000000e+00 0.000000e+00 6.000000e-01
1.000000e+00 0.000000e+00 -2.300000e+00
1.000000e+00 0.000000e+00 4.700000e+00
1.000000e+00 0.000000e+00 1.000000e+00
1.000000e+00 0.000000e+00 4.500000e+00
1.000000e+00 0.000000e+00 4.000000e+00
1.000000e+00 0.000000e+00 2.700000e+00
1.000000e+00 0.000000e+00 1.700000e+00
1.000000e+00 0.000000e+00 2.700000e+00
1.000000e+00 0.000000e+00 3.900000e+00
0.000000e+00 1.000000e+00 -4.000000e+00
0.000000e+00 1.000000e+00 3.000000e+00
0.000000e+00 1.000000e+00 -1.300000e+00
0.000000e+00 1.000000e+00 -5.300000e+00
0.000000e+00 1.000000e+00 6.000000e-01
0.000000e+00 1.000000e+00 -2.000000e-01
0.000000e+00 1.000000e+00 -2.300000e+00
0.000000e+00 1.000000e+00 -3.800000e+00
0.000000e+00 1.000000e+00 -2.000000e+00
0.000000e+00 1.000000e+00 -4.200000e+00
0.000000e+00 1.000000e+00 -4.700000e+00
0.000000e+00 1.000000e+00 1.200000e+00
-Rajkumar
Wayne State University
Detroit.
-----Original Message-----
From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf
Of Steve Smith
Sent: Wednesday, April 23, 2008 4:24 PM
To: [log in to unmask]
Subject: Re: [FSL] TBSS
Hi - please see the TBSS and randomise manual!
Cheers.
On 22 Apr 2008, at 16:58, Rajkumar wrote:
> Hi,
> We are trying to create design matrix and contrast files
> for our TBSS analysis which involved 18 study subjects and 13
> control subjects. Kindly suggest how we can include age of the
> individual subjects as a covariate in the final group analysis.
> Thanks.
> -Rajkumar
>
>
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Stephen M. Smith, Professor of Biomedical Engineering
Associate Director, Oxford University FMRIB Centre
FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK
+44 (0) 1865 222726 (fax 222717)
[log in to unmask] http://www.fmrib.ox.ac.uk/~steve
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