Dear All

We are re-advertising this position. It is ideally suited to a statistician 
with interest in applications in Medicine, willing to work in a dynamic and 
competitive group.

We will appreciate if you can pass it on to possible candidates not on the 
list.

Thanks,

Renee Menezes.
_____________________________________________________________________

The department of Pediatrics – group of Pediatric Oncology/Hematology of 
the Erasmus Medical Centre, Rotterdam, has an open position for a 

Biostatistician/Bioinformatician
With a PhD degree


THE DEPARTMENT – In the Pediatric Oncology/Hematology Department of the 
Erasmus MC-Sophia Children’s Hospital, headed by Prof. Rob Pieters, the 
research program on “Biological determinants of leukemogenesis and clinical 
outcome and development of targeted therapies in childhood cancer” is 
central. The research, mostly executed in the research laboratory led by 
Dr. Monique L. den Boer, is directed towards (epi)genetic aberrations and 
the molecular biology of cancer cells, aiming at improving treatment of 
children with cancer. This work forms a bridge between research and clinic 
and generates publications in important journals in oncology, as well as 
intensive collaborations with other international research laboratories. 
The group currently has one part-time biostatistician.

FUNCTION DESCRIPTION – Within this research programme we have a position 
for a biostatistician/ bioinformatician, who will be responsible for the 
data analysis  related to the use of –omics data in the search for genes 
and proteins that can be used to improve the diagnosis and treatment of 
pediatric leukemia and solid tumors. Specific types of data collected are 
high-throughput DNA, RNA and protein profiles from several patient groups. 
The research will involve not only analyzing these data types individually, 
but also searching for associated patterns between them. The person 
appointed will also be involved in a new project to study the behaviour of 
biological pathways using DNA, microRNA and RNA data.

DESIRED PROFILE – PhD in Statistics with work experience in applications to 
Biology, or PhD in Biology/related subject with strong statistical content. 
Enthousiastic, precise person able to work independently and as part of a 
group. Ability to present results clearly orally as well as in writing to 
non-statisticians is essential. Ability to work in various projects 
efficient and simultaneously. Programming experience in statistical 
environments is essential, experience with S-Plus/R highly desirable. Good 
knowledge of English is essential, Dutch knowledge not essential. Previous 
experience of complex data analysis may be an advantage.  

WORK CONDITIONS – Salary depending upon qualification, skills and 
experience. The appointment is for a full-time position with duration of 2 
years, with extension possible depending on progress.

HOW TO APPLY – Your application letter with CV and motivation letter may be 
sent to Dr. M.L. den Boer Erasmus MC-Sophia, Dept Pediatrics, 
Oncology/Hematology, room Sp2456, Postbus 2060, 3000 CB Rotterdam, The 
Netherlands. For more information please contact Renée X. de Menezes using 
the e-mail [log in to unmask]

DEADLINE FOR APPLICATIONS: 23rd May 2008