Dear Peter,
Thank you a lot for your email.
I can do without the automation (will do manual identification of affected
tissue), but I would like to have my FLAIR images in the MNI space. Do you
know if anyone does such registration with 5mm slice thickness? I know you
had 1mm isovoxel in your recent study and others with my parameters just do
manual tracing on FLAIR image + multiply by slice gap to get the WMH volume.
Do you know if I will get this registration well in FLIRT and my MPRAGE or
shall I use a 1x1x1 T1-WI of these subjects (I may get them, but acquired in
different MRI session- or will it cause even more problems with my FLAIR
quality?). I am not too familiar with FLIRT yet.
Thanks a lot,
Aga
On 18.03.2008 14:33 Uhr, "Peter Kochunov" <[log in to unmask]> wrote:
> Aga,
>
> Unfortunatly, I don't think automated processing will be possible with this
> dataset. The only workable approach to do automated HWM lesion segmentation
> is by the use of T2-maps produced by the multi-echo sequences.
> pk
> ----- Original Message -----
> From: "Agnieszka Burzynska" <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Tuesday, March 18, 2008 7:09 AM
> Subject: [FSL] White matter hyperintensity and FLAIR processing
>
>
>> Dear all,
>> I am searching for the most straightforward way to estimate the WMH load
>> in
>> my subjects.
>> 1) Was there any follow-up on the message from 2002? (see below)
>> 2) My FLAIR images have resolution 1.3x0.9x5mm and my MPRAGE 2x2x1mm. Does
>> it mean I will have hard time in registering them to MNI?
>>
>> Thank you!
>>
>> Aga
>>
>>
>> On Mon, 22 Jul 2002, Wei Wen wrote:
>>
>>> Dear Steve,
>>>
>>> It may be possible to extract (segment) white matter hyperintensity
>>> (FLAIR
>>> sequence) using a combination of bet, fast etc. as discussed at FSL
>>> course
>>> in Melbourne. Could I send you a couple of such images and see if you
>>> could
>>> tweak the programs (or come up with some suggestions) for this purpose?
>>>
>>> Many thanks,
>>>
>>> Wei Wen
>>> NPI, Prince of Wales Hospital/UNSW
>>> Australia
>>>
>>>
>>
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