POSTDOCTORAL POSITION AVAILABLE
A postdoc position is available at Case Western Reserve
University in the structural biology lab of
Dr. Focco van den Akker. The project is funded by NIH
and involves structure-function studies of cyclic nucleotide
signaling pathways. These pathways are involved in processes
such as regulation of blood pressure and bone growth; a
number of proteins in this pathway are drug targets for
treating hypertension and congestive heart failure. One of
the classes of proteins we are targeting for structure-function
studies are guanylyl cyclases (Ma et al., EMBO J, 26, p578-;
Ma et al., JBC, 283, p1167-; Sayed et al., PNAS, 104, p12312-;
van den Akker et al., Nature 406, p101-). See website for details:
http://daspot.bioc.cwru.edu/Focco/project1.html
Other proteins in this pathway are targeted as well in
collaboration with a number of academic and pharmaceutical
partners. The goal of this project is to delineate the
molecular signaling events of these pathways using a
multi-disciplinary approach with an emphasis on crystallography,
and to exploit these insights for therapeutic modulation.
Access to state-of-the-art equipment and facilities are
available including a newly-installed Rigaku Micromax-007
ccd diffraction system.
Applications will be accepted from highly motivated individuals
who have recently obtained their Ph.D. (less than 4 years).
The applicant should have experience in either molecular
biology or protein biochemistry (experience in protein
crystallography is not required but is desirable).
The position is open immediately and salary will be commensurate
with qualifications and experience. Please send cover letter,
CV, and list of 3 references to: [log in to unmask]
Focco van den Akker, Ph.D.
Assistant Professor
Department of Biochemistry/RT500
Case Western Reserve University
10900 Euclid Avenue
Cleveland, OH 44106
Website: http://daspot.bioc.cwru.edu/Focco/
The Case Western Reserve University is an Equal
Opportunity/Affirmative Action employer.
|