Matt,
Thanks for your reply.
We are very new to the DTI analysis and currently trying to understand the
tracking algorithm used by FSL. We are mapping a few anatomically well known
tracts to investigate the results. Some of our tracts do look anatomically
correct, however, others, like the corticospinal tract do no exhibit proper
anatomical architecture. We are not sure at this point whether it is our
acquisition or processing that is causing this issue.
The corticospinal tract is generated by the seed in the L posterior limb of
the internal capsule and a waypoint mask of medullary reticulospinal
formation in the structural space. We select the structural to diffusion
transform when running the probrackx and use Euler intergration with
pre-specified settings. The resulting tract does go through the posterior
limb of IC and down the brainstem, but the cortical connections are very
sparse with a low number of streamlines traveling through them.
If you have any insights as to what might be causing the problem in the
fiber distribution they will be greatly appreciated.
Anastasia
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