Hi - if you want to try testing FA away from where the skeleton is
found in TBSS, then you can indeed try just feeding all_FA into the
voxelwise stats with randomise.
The obvious danger is that you are susceptible to alignment
differences, i.e. the issue that the skeleton-projection stage in TBSS
attempts to resolve. If you are doing a two-group comparison, it is
important (for example) to create separate group mean FA images (using
the data in all_FA) to check for systematic alignment differences.
Cheers, Steve.
On 14 Feb 2008, at 20:32, Adrian Koziak wrote:
> Thanks for the info. I looked at VBM, but I thought that it only
> applies to
> T1-weighted anatomical images.
>
> Would it be reasonable for me to apply fslVBM to the B zero image in
> my DTI
> data sets and then apply this transform to my DTI-FA data ?? If so,
> how can
> I carry over the transformations to the FA data ?
>
> If not the B zero image, can I apply the transforms to my T1-weighted
> anatomicals and then apply these tranforms to the FA data?
>
> I am looking at FA values in these regions, not morphometric
> differences.
>
>
> Thank you very much for your response
>
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Stephen M. Smith, Professor of Biomedical Engineering
Associate Director, Oxford University FMRIB Centre
FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK
+44 (0) 1865 222726 (fax 222717)
[log in to unmask] http://www.fmrib.ox.ac.uk/~steve
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