Hi Joyce
The most appropriate statistical method is a z-value transformation. I
recommend to produce a mean and sd image from your control subjects and the
compute voxel-wise z-values by z = ((FA map patient - mean FA map
controls)/(sd FA map controls)). Then you can threshold this map.
Best regards
Juergen
PS: I would not restrict the FA values only on the skeleton produced by
TBSS. Instead leave the TBSS stream after tbss_3_postreg and analyze the
whole brain, i.e. All FA values > 2000.
Regards
Juergen
On 30.1.2008 8:59 Uhr, "[log in to unmask]" <[log in to unmask]> wrote:
> Hi all,
>
> I have one patient (n=1) and would like to compare his FA with
> a group of controls (n=5).
> I have been through all tbss steps as described in
> http://www.fmrib.ox.ac.uk/fsl/tbss/index.html (using the
> template FMRIB58 for corregistration).
> I am now ready to run the statistics but I am not sure about
> which procedure is the correct one. My problem is that I am
> trying to compare 1 patient with a whole group.
> Does anyone know which test can give me a map of FA differences
> between the patient and controls?
>
> I thank you in advance,
>
> Peace,
> Joyce!
-----------------------------------------------------------
Juergen Haenggi
Ph.D. (Dr. des.)
Division of Neuropsychology
Institute of Psychology
University of Zurich
Binzmuehlestrasse 14, PO Box 25
8050 Zurich, Switzerland
0041 44 635 73 97 (phone office)
0041 76 445 86 84 (phone mobile)
0041 44 635 74 09 (fax office)
BIN 4.D.04 (office room number)
[log in to unmask] (email)
http://www.psychologie.uzh.ch/neuropsy/ (website)
http://www.juergenhaenggi.ch (private website)
-----------------------------------------------------------
|