Andy Lee wrote:
> ----- Original Message ----
> From: Paul Bromley <[log in to unmask]>
> >From past experience I have found Atorva 10 to be very effective. Additionally what is the rationale for switching those with side effects to Pravastatin?
>
> Seems to be a widespread belief about Atorva 10 but when we switched large group from that to Simva 20, almost all remained at least as well controlled, some even better and very few needed increase to 40.
>
It depends what you are trying to do - and the evidence base that exists.
Reach cholesterol targets or prevent strokes and heart attacks.
Simva 40 has the evidence base for preventing nasty things
Simva 20 (and the OTC 10) doesn't
Similarly Rosuva doesn't have the evidence base for saving lives or the
safety record.
Jeff
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