PISA gives a good analysis of a known interface, but won't predict it
from scratch. So basically you need a protein-protein docking program of
which there are several:
3DDock, gramm, zdock, etc, etc
There's a review in G.R.Smith and MJE Sternberg, Curr Opion Struct Biol,
12, 28 (2002) - obviously a little old now.
See also the CAPRI assessment http://capri.ebi.ac.uk/
These methods will give you a surfeit of predictions, the fun is in
choosing the one you like, e.g. using tools like PISA
HTH
Martyn
On Thu, 2007-11-29 at 12:47 +0000, Andreas Förster wrote:
> Hey Karen,
>
> Pisa analyzes oligomerization interfaces.
> http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html
>
>
> Andreas
>
>
> karen yates wrote:
> > Hi,
> >
> > I would like to find a bioinformatic tool that will allow me to predict the
> > dimerisation interface of a protein.
> >
> > A structural model has been generated, and it is known to exist as a homo-dimer.
> >
> > Does anyone know of a suitable program?
> >
> > Thank you for your help.
> >
> > Karen
> >
> >
> >
> > ----------------------------------------------------------------
> > This message was sent using IMP, the Internet Messaging Program.
> >
--
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