University of Dundee

College of Life Sciences
Division of Biological Chemistry and Drug Discovery

Research positions

Enthusiastic and highly motivated individuals are sought to study key  
enzymes of microbial pathogens. In particular to advance fundamental  
understanding of biosynthesis and inhibition of trypanothione and  
glycosylphosphatidylinositol  biosynthesis in trypanosomatid  
parasites. The positions are funded by a Wellcome Trust programme  
grant and to be held in a world-class interdisciplinary centre.
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Postdoctoral Research Assistants (3 posts) – LS/1906
Grade 7 (£26,666 - £32,796)

Postdoctoral Research Assistants are required to characterise the  
structure-function relationships of important biosynthetic enzymes  
essential in trypanosomatid parasites. Applicants are expected to  
have experience in structural or molecular biology, biochemistry or  
chemical crystallography. Experience in production of proteins in  
eukaryotic systems would be particularly welcome.
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Postdoctoral Research Assistant – LS/1907
Grade 7 (£26,666 - £32,796)

Postdoctoral Research Assistant who will prosecute inhibitor  
discovery employing structure-based methods and high-throughput  
screening against validated therapeutic targets from microbial  
pathogens. Experience in assay development, computational chemistry  
and molecular modelling, or crystallography would be beneficial.
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RESEARCH Technician – LS/1908
Grade 5 (£18,165 - £21,050)

Responsible for protein production in support of high-throughput  
chemical screening and structural biology.  Applicants are expected  
to be educated to a degree level in a science subject and should have  
2-3 years relevant laboratory experience.
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All posts are available for two years in the first instance. The  
level of appointment is flexible and will depend on experience and  
track record. For postdoctoral positions applicants are expected to  
have, or to obtain shortly, a PhD in a relevant subject.  Training,  
as required will be provided in a supportive environment enabling  
researchers to extend their skills and expertise.  Career progression  
is important and staff will be encouraged to participate in a wide  
range of research, and in this the ability to work well in a team  
will be critical.

The successful candidates will benefit from access to cutting edge  
facilities in crystallography, biochemistry, cell biology, synthetic  
and medicinal chemistry, parasitology, drug discovery, proteomic and  
other core facilities. In addition to joining the Scottish Structural  
Proteomics Facility, a highly successful cooperative with The  
University of St. Andrews.

Informal enquiries may be made to Prof Bill Hunter, e-mail:  
[log in to unmask] (Please do not send applications to this  
email address).

A few facts about The College of Life Sciences at Dundee:

The College of Life Sciences has over 720 research and support staff  
from 53 countries and an annual research turnover in excess of £20  
million.
According to Thompson Scientific of Philadelphia, based on citations  
per paper over the last 10 years, Dundee is the top University in  
Europe in ‘Biology and Biochemistry’ and 2nd in Europe in ‘Molecular  
Biology and Genetics’.
Dundee has twice been named ‘the best place to work in Europe’ in a  
poll of scientists conducted by The Scientist magazine.
The College of Life Sciences has been consistently rated ‘5-
star’ (the highest rating) by the UK national Research Assessment  
Exercise.

In addition to an excellent scientific environment Tayside offers an  
affordable standard of living in an area of outstanding natural  
beauty situated beside the sea and the highlands of Scotland.

Applications in the form of a CV and covering letter (2 copies of  
each), including the names and addresses of 3 referees, should be  
sent to Human Resources, College of
 Life Sciences, JBC/MSI/WTB  
Complex, University of Dundee, [log in to unmask]) quoting the appropriate reference number.

Applicants will only be contacted if invited for interview.

Closing date:  28th September 2007

The University of Dundee is committed to equal opportunities and  
welcomes applications from all sections of the community.

www.jobs.dundee.ac.uk

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W. N. Hunter
Professor of Structural Biology, FRSE
Div. of Biological Chemistry & Drug Discovery
College of Life Sciences
Univ. of Dundee
Dundee
DD1 5EH
ph: (0)1382-385745