At 13:36 28/08/2007, you wrote:
>I've recently had a couple of patients where they have a markedly raised
>ferritin, but relevant investigations are normal. In these cases, ferritin
>appears to be acting as an acute phase reactant (like ESR/CRP/Plasma
>viscocity)
>- one patient has rheumatoid arthritis, and looking back, raises in
>her Ferritin
>have also gone hand in hand with a rise in ESR and deterioration clinically in
>her rheumatoid. The other patient had Crohn's, and higher levels seemed to be
>associated with deterioration in her Crohn's (and in this case, it was a more
>sensitive indicator of problems than either ESR or CRP).
>
>Laurie Miles
http://stemcells.alphamedpress.org/cgi/content/full/15/4/291
"Serum ferritin protein is an acute phase reactant."
Sadly not an original discovery, but a gold * for observation :)
Julian
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