Research Technician (Fixed-term)
Protein expression for Structural Biology
Applications are invited for the above post from highly motivated individuals with a strong interest in eukaryotic protein expression, protein biochemistry and protein purification. The research project is funded by the British Heart Foundation as part of a programme grant to study blood coagulation factors. A thorough understanding of these factors will lead to the design of inhibitors targeted at thrombosis related disease. The successful candidate will use insect cell expression systems to express soluble proteins and purify these for crystallisation and fluorescence (FRET) experiments.
The person appointed will benefit from both state-of-the-art facilities in the crystallography laboratory and the collaborative environment of the Centre for Biomolecular Sciences located on the University Park campus. Facilities include AKTA protein purification equipment, a 10L Fermentor, nanolitre dispensing crystallisation robotics, and a modern high flux X-ray data collection. This post is based within the Division of Medicinal Chemistry and Structural Biology in the School of Pharmacy at the University of Nottingham.
Candidates should ideally have a degree or equivalent qualification from the biological sciences. Experience with tissue culture, protein purification and preferably insect cell expression systems and/or baculovirus is desirable.
Salary will be within the range £19,264 - £23,002 per annum, depending on qualifications and experience (salary can progress to £27,466 per annum, subject to performance). This post is available from 1st October 2007 and will be offered on a fixed-term contract for a period of five years.
Informal enquiries may be addressed to Dr J Emsley, Email: [log in to unmask]
Candidates should send a detailed CV, together with the names and addresses of two referees, to Dr J Emsley, Centre for Biomolecular Sciences, The University of Nottingham, University Park, Nottingham NG7 2RD. Email: [log in to unmask] Please quote ref. SCI/251.
Dr Jonas Emsley
Associate Professor and Reader in Crystallography,
Division of Medicinal Chemistry & Structural Biology,
Centre for Biomolecular Sciences,
School of Pharmacy,
University of Nottingham,
University Park,
Nottingham.
NG72RD
Tel: +44 1158467092
Fax: +44 1158468002
email:[log in to unmask]
http://www.nottingham.ac.uk/pharmacy/stafflookup/staff-by-role.php?id=ODA0MzI5&page_var=personal
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