> If your Phaser results show a high Z-score (> 8) AND high LLG AND your
> solution packs without clashes AND refines (even though starting R/Rfree
> is high) AND reproduces density for the model portion AND produces some
> Fo-Fc density for the missing portion, most probably your solution is
> correct.
AND the z-score for your solution stands out from the z-scores for
incorrect (/other) solutions. I've gotten z-scores > 8 for a known
incorrect solution while testing (searching for a domain not present in
the crystal, so this test was probably unrealisticly difficult). The
highest/second highest z-scores for the incorrect domain were roughtly
equal (~8.7/~8.2); for the correct domain they were ~ 35/7).
So as long as you're checking phaser statistics, this is another one to
check.
Pete
Pete Meyer
Fu Lab
BMCB grad student
Cornell University
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