Hi Roland,
sounds like a mail for me :)
> 1. There is the new origin by center of mass option in the vbm5.1 beta
> toolbox. While this is great for batch processing I wonder if it has
> qualitative advantages over manually setting the origin to AC. So what would
> you advice especially for children templates?
I think the main idea is to porovide better starting estimates for the
registration that follows. If you want to go through the pain of setting
the origin to the AC in every case, that will likely be even better, but
depending on the number of subjects... I do not think that this has any
special bearing on pediatric templates, although one could speculate
that the changing non-brain tissue will also change the center of mass,
but hey, there's always something :)
> 2. If the origin is set by one of the above methods, what kind of affine
> transformation would you recommend: "ICBM", "average Brain" or "none"
I think that these settings are not necessarily to be seen in
conjunction... or in other words, 1 is likely a good idea regardless of
2, which again depends on your template. If you use custom ones,
"average brain" might be the best alternative.
Bet,
Marko
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Marko Wilke (Dr.med./M.D.)
[log in to unmask]
Universitäts-Kinderklinik University Children's Hospital
Abt. III (Neuropädiatrie) Dept. III (Pediatric neurology)
Hoppe-Seyler-Str. 1, D - 72076 Tübingen
Tel.: (+49) 07071 29-83416 Fax: (+49) 07071 29-5473
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